Bioactivity | Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Ar TFA is a fluorogenic renin substrate based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP)[1]. | ||||||
Name | Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg TFA | ||||||
Sequence | Arg-{Glu-edans}-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-{Lys-dabcyl}-Arg | ||||||
Shortening | R-{Glu-edans}-IHPFHPFHLVIHT-{Lys-dabcyl}-R | ||||||
Formula | C131H180F3N37O26S | ||||||
Molar Mass | 2778.12 | ||||||
Appearance | Solid | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
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Reference | [1]. Katherine Paschalidou, et al. Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions. Biochem J. 2004 Sep 15;382(Pt 3):1031-8. |