Bioactivity | Arg-Arg-AMC is a highly selective substrate of Cathepsin B. Arg-Arg-AMC can be used to cathepsin B activity assay in cancer cells, while cathepsin B is assocaited with cell invasive and metastatic phenotype in numerous types of cancer[1]. |
Target | Cathepsin B |
Name | Arg-Arg-AMC |
CAS | 263843-55-6 |
Sequence | Arg-Arg-{AMC} |
Shortening | RR-{AMC} |
Formula | C22H33N9O4 |
Molar Mass | 487.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hulkower KI, et al. Fluorescent microplate assay for cancer cell-associated cathepsin B. Eur J Biochem. 2000 Jul;267(13):4165-70. |