| Bioactivity | Apoptosis inducer 4 (Compound 12b) is an apoptosis inducer with anticancer activities[1]. |
| Invitro | Apoptosis inducer 4 (Compound 12b) (0-50 µM, 72 h) shows antiproliferative activities against cancer cells without obvious cytotoxicity against normal cells[1].Apoptosis inducer 4 (0-2 µM, 48 h) causes cell cycle arrest at S phase in K562 cells and G1 phase in HepG2 cells[1].Apoptosis inducer 4 (0-4 µM, 24 and 48 h) induces pyknosis in K562 cells, and induces mitochondrial membrane potentials decline[1].Apoptosis inducer 4 (0-2 µM, 72 h) induces apoptosis in K562 and HepG2 cells[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Apoptosis inducer 4 |
| CAS | 2408050-83-7 |
| Formula | C41H50O11S3 |
| Molar Mass | 815.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |