| Bioactivity | Ap4A tetraammonium (P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium) is a conserved second messenger in organisms ranging from bacteria to humans. Ap4A tetraammonium binds to the histidine triad nucleotide-binding protein 1 (HINT1) activates the transcription of genes downstream of MITF. Ap4A tetraammonium induces apoptosis[1][2]. |
| Invitro | Ap4A tetraammonium (1, 10 µM; 24 h) 诱导 HL60 细胞凋亡[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Ap4A tetraammonium 相关抗体: |
| CAS | 102783-36-8 |
| Formula | C20H40N14O19P4 |
| Molar Mass | 904.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yu J, et al. Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells. Nat Commun. 2019 Oct 11;10(1):4664. [2]. Vartanian A, et al. Ap4A induces apoptosis in human cultured cells. FEBS Lett. 1999 Jul 30;456(1):175-80. |
Ap4A tetraammonium
CAS: 102783-36-8 F: C20H40N14O19P4 W: 904.51
Ap4A tetraammonium (P1,P4-Di-(adenosine-5')-tetraphosphate tetraammonium) is a conserved second messenger in organisms r
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