| Bioactivity | Antitumor agent-109 (compound 6) is an inhibitor of hyaluronic acid (HY-B0633A) targeting to CD44, as well as an anti-tumor agent. Hyaluronic acid interacts with differentiation cluster 44 (CD44) and is involved in tumor growth and invasion. Antitumor agent-109 inhibits MDA-MB-231 cells with EC50 value of 0.59 μM[1]. |
| Target | Hyaluronic acid |
| Name | Antitumor agent-109 |
| Formula | C19H22BrNO3 |
| Molar Mass | 392.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570. |
Antitumor agent-109
CAS: F: C19H22BrNO3 W: 392.29
Antitumor agent-109 (compound 6) is an inhibitor of hyaluronic acid (HY-B0633A) targeting to CD44, as well as an anti-tu
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.