Bioactivity | 9-Amino-NeuAc is a substrate of synthase. 9-Amino-NeuAc can be converted to CMP9-amino-NeuAc, activated to the corresponding CMPglycoside and transferred to asialoglycoprotein. 9-Amino-NeuAc can be used to target liposome synthesis while modulating tumor surface immunogenicity[1][2]. |
Name | 9-Amino-NeuAc |
CAS | 153232-60-1 |
Formula | C11H20N2O8 |
Molar Mass | 308.29 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zheng N, et al. Liposome-aided metabolic engineering of tumor surface immunogenicity. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2550-2554. [2]. Gross H J, et al. Asialo-伪 1-acid glycoprotein resialylated with 9-amino-5-N-acetyl-d-neuraminic acid is resistant towards bacterial, viral and mammalian sialidases[J]. Glycoconjugate Journal, 1988, 5: 411-417. |