| Bioactivity | Antitumor agent-104 (Compound 9) is an antitumor agent by inhibiting DNA damage repair in tumors. Antitumor agent-104 inhibits PARP1 enzymatic activity and the PAR protein level. Antitumor agent-104 also inhibits the expression of CDK12[1]. |
| Name | Antitumor agent-104 |
| CAS | 2245272-16-4 |
| Formula | C31H33FN6O3 |
| Molar Mass | 556.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lin S, et al. Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers. ACS Omega. 2023 Jul 7;8(28):25574-25581. |
Antitumor agent-104
CAS: 2245272-16-4 F: C31H33FN6O3 W: 556.63
Antitumor agent-104 (Compound 9) is an antitumor agent by inhibiting DNA damage repair in tumors. Antitumor agent-104 in
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