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Antitubercular agent-29

CAS: F: C20H12ClN3O5 W: 409.78

Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with M
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Bioactivity Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 µg/mL against drug-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 µg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells[1].
Target MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb
Name Antitubercular agent-29
Formula C20H12ClN3O5
Molar Mass 409.78
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kumar Sahoo S, et al. Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. Bioorg Med Chem. 2022 Jun 15;64:116777.