| Bioactivity | Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 µg/mL against drug-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 µg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells[1]. |
| Target | MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb |
| Name | Antitubercular agent-29 |
| Formula | C20H12ClN3O5 |
| Molar Mass | 409.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kumar Sahoo S, et al. Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. Bioorg Med Chem. 2022 Jun 15;64:116777. |