| Bioactivity | Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC50s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer[1]. |
| Invitro | Antiproliferative agent-11 (0-100 μM; 72 h) exhibits antiproliferative activity to MCF-7, HeLa, 518A2, HCT116 and RD[1].Antiproliferative agent-11 (26.8 μM; 24 h) induces apoptosis in HCT116 cells[1].Antiproliferative agent-11 (10-26.8 μM; 72 h) promotes HCT116 cells death by a mitochondria-dependent mechanism[1].Antiproliferative agent-11 (0-50 μM; 24 h) inhibits HCT116 cells under 3D cell culture conditions[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Antiproliferative agent-11 |
| Formula | C31H34Cl2N6O3P2Ru |
| Molar Mass | 772.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Antiproliferative agent-11
CAS: F: C31H34Cl2N6O3P2Ru W: 772.56
Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane comple
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