Bioactivity | Antimicrobial agent-28 (Compound Bicycle molecule) is an antibacterial agent with good affinity for the penicillin-binding protein (PBP3) of Escherichia coli, which can inhibit the activity of Escherichia coli[1]. |
Sequence | Ala-Cys-Ser-Phe-Pro-Lys-Cys-Pro-Trp-Val-Glu-Gly-Cys-Ala-NH2 (TATA covalent with Cys2,Cys7,Cys13) |
Shortening | ACSFPKCPWVEGCA-NH2 (TATAcovalentwithCys2,Cys7,Cys13) |
Formula | C78H112N20O20S3 |
Molar Mass | 1746.04 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rowland C E, Newman H, Martin T T, et al. Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle®) Antimicrobial Inhibitor of Escherichia coli PBP3[J]. bioRxiv, 2024: 2024.03. 20.581580. |