Antifungal agent 59_product_DataBase

Bioactivity	Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety[1].
Invitro	Antifungal agent 59 (compound A23) 显示体外抗真菌活性，MIC 值为 0.02 μg/mL (白色念珠菌)、0.01 μg/mL (白色念珠菌)、0.25 μg/mL (玉米酵母念珠菌)、0.25 μg/mL (新型隐球菌)、0.06 μg /mL (克氏念珠菌)、1 μg/mL (光滑念珠菌)、0.02 μg/mL (近光滑念珠菌) 和 1 μg/mL (烟曲霉)[1]。Antifungal agent 59 (0.02 μg/mL ;48 h) 有效杀灭白色念珠菌[1]。Antifungal agent 59 (1-16 μg/mL) 对兔红细胞具有溶血活性，浓度为 8 μg/mL 时溶血率为 93.47%[1]。
Name	Antifungal agent 59
CAS	2422019-96-1
Formula	C18H15BrF2N2Se
Molar Mass	456.19
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

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