Antifungal agent 47_product_DataBase

Bioactivity	Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide[1].
Invitro	Antifungal agent 47 (compound 3b) 对五种植物病原真菌（P. capsici、R. solani、B. cinerea、P. aphanidermatum 和 S. sclerotiorum)具有杀菌活性，EC50 值分别为 12.70、21.74、22.42、11.00 和 4.78 μM[1]。Antifungal agent 47 (35 μM, 3 h) 抑制 P. capsici 菌丝体的 ATP 产生，抑制率为 61.70±3.64%[1]。Antifungal agent 47 对线粒体的作用大大改善，如通过破坏病原体的线粒体功能，引起线粒体肿胀，减弱其对细胞壁形态的影响等[1]。
In Vivo	Antifungal agent 47 (compound 3b) (200 μg/mL) 显示出对番茄果实中 B. cinerea 的杀真菌活性[1]。 Animal Model:
Name	Antifungal agent 47
Formula	C39H38BrClNO2P
Molar Mass	699.06
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Yin F, et al. Triphenylphosphonium-Driven Targeting of Pyrimorph Fragment Derivatives Greatly Improved Its Action on Phytopathogen Mitochondria. J Agric Food Chem. 2023 Feb 15;71(6):2842-2852.

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