| Bioactivity | Anticancer agent 101 is a derivative of tetracaine. Anticancer agent 101 has anti-cancer activity[1]. |
| Invitro | Anticancer agent 101 (compound 2m; 24 and 48 h) 具有抗肿瘤活性，对 Colo-205 和 HepG2 细胞的 IC50 值分别为 20.5 μM 和 62.9 μM[ 1].Anticancer agent 101 (25 µM 和 50 µM; 24 h) 下调了 Colo-205 细胞中凋亡蛋白 PI3K 和 FoXO3a 的表达水平，上调了 PTEN 和 FoXO1 的表达水平。 Cell Viability Assay[1] Cell Line: |
| Name | Anticancer agent 101 |
| CAS | 2914922-80-6 |
| Formula | C19H20F3N3O |
| Molar Mass | 363.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M İhsan Han, et al. Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones. ACS Omega. 2023 Feb 28;8(10):9198-9211. |