Antibacterial agent 83_product_DataBase

Bioactivity	Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].
Invitro	Antibacterial agent 83 (compound 17h) 对 Newmana、USA300b、Mu50 均有抗菌作用，MIC 均为0.25 μg/mL[1]。Antibacterial agent 83 在大鼠、小鼠和犬肝微粒体中稳定性较差[1]。
Name	Antibacterial agent 83
CAS	2413865-92-4
Formula	C11H5Cl2N3O2
Molar Mass	282.08
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Huan X, et al. Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm. Eur J Med Chem. 2022 Jun 5;236:114309.

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