| Bioactivity | Antibacterial agent 255 (compound (±)-1) is a potent antibacterial agent. Antibacterial agent 255 is a potent and selective 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE) inhibitor with IC50 values of 13.0, 8.0, 20 µM for EclspE, KplspE, AblspE, respectively[1]. |
| Target | IC50: 13.0 µM (EclspE); 8.0 µM (KplspE); 20 µM (AblspE) |
| CAS | 945980-50-7 |
| Formula | C14H18N4O3S2 |
| Molar Mass | 354.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hamid R, et al. IspE kinase as an anti-infective target: Role of a hydrophobic pocket in inhibitor binding. Structure. 2024 Nov 1:S0969-2126(24)00444-1. |
Antibacterial agent 255
CAS: 945980-50-7 F: C14H18N4O3S2 W: 354.45
Antibacterial agent 255 (compound (±)-1) is a potent antibacterial agent. Antibacterial agent 255 is a potent and selec
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