Antibacterial agent 207

CAS: F: C61H56F12N8O3P2Ru W: 1340.15

Antibacterial agent 207 (Compound Ru1) has antibacterial activity against S. aureus (MIC: 1 μg/mL), and low resistance

Contact QiTai

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Antibacterial agent 207 (Compound Ru1) has antibacterial activity against S. aureus (MIC: 1 μg/mL), and low resistance frequencies. Antibacterial agent 207 destroys the bacterial cell membrane, promote production of ROS in bacteria[1].
Invitro	Antibacterial agent 207 (1 和 2 μg/mL) 显示出对金黄色葡萄球菌细菌膜的损伤（PI染色），并诱导 β-半乳糖苷酶的释放[1]。Antibacterial agent 207 (1 和 2 μg/mL，2 小时) 会引起一系列氧化应激损伤，在金黄色葡萄球菌中诱导 ROS[1]。Antibacterial agent 207 (0.25 或0.5 μg/mL，48 小时) 抑制金黄色葡萄球菌中 α-毒素的分泌和细菌生物膜的形成[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 207 相关抗体:
In Vivo	Antibacterial agent 207 ( 5mg/kg，5 μL，在右侧腹足注射) 显示出抗感染作用并增加感染金黄色葡萄球菌的蜡螟 (G. mellonella) 的存活率[1]。Antibacterial agent 207 (100μg/mL，涂抹于伤口，每天两次) 对感染金黄色葡萄球菌的小鼠皮肤中金黄色葡萄球菌具有很强的抗感染功效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Formula	C61H56F12N8O3P2Ru
Molar Mass	1340.15
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Wang L, et al. Design, synthesis, anti-infective potency and mechanism study of novel Ru-based complexes containing substituted adamantane as antibacterial agents. Eur J Med Chem. 2024 Apr 2;270:116378.