| Bioactivity | Antibacterial agent 200 (pyridyl HH 7), a unique hydrazyl hydroxycoumarin (HH), has strong antibacterial efficacy and broad antibacterial spectrum with MIC values ranging from 0.5 to 32 μg/mL for Gram-positive and Gram-negative bacteria. Antibacterial agent 200 exhibits a good inhibition against Pseudomonas aeruginosa 27853 with a low MIC value of 0.5 μg/mL. Antibacterial agent 200 can eradicate the integrity of bacterial membrane, result in the leakage of intracellular proteins, and interact with bacterial DNA gyrase via non-covalent binding[1]. |
| Formula | C16H11N3O4 |
| Molar Mass | 309.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiang-Sheng Zhao, et al. Hydrazyl hydroxycoumarins as new potential conquerors towards Pseudomonas aeruginosa. Bioorg Med Chem Lett. 2024 May 1:103:129709. |
Antibacterial agent 200
CAS: F: C16H11N3O4 W: 309.28
Antibacterial agent 200 (pyridyl HH 7), a unique hydrazyl hydroxycoumarin (HH), has strong antibacterial efficacy and br
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