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Antibacterial agent 154

CAS: 2163048-45-9 F: C25H28ClFN4O5 W: 518.97

Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent.
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Bioactivity Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent. Antibacterial agent 154 inhibits Gram-positive and Gram-negative bacteria. Antibacterial agent 154 demonstrated in vivo efficacy in a mouse model of staphylococcal sepsis[1].
Invitro Antibacterial agent 154 (compound 7) 抑制革兰氏阳性菌 M. luteus,B. subtilis,S. aureus,S. epidermidis 的 MIC 分别为 4 μg/mL,2 μg/mL,2 μg/mL,2 μg/mL;抑制革兰氏阴性菌 P. aerugenosa,E. coli,S. typhimurium 的 MIC 分别为 2 μg/mL 和 2 μg/mL[1]。 0 --> Antibacterial agent 154 相关抗体:
Name Antibacterial agent 154
CAS 2163048-45-9
Formula C25H28ClFN4O5
Molar Mass 518.97
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Shtyrlin NV, et al. Synthesis and biological evaluation of fluoroquinolones containing a pyridoxine derivatives moiety. Eur J Med Chem. 2023 Sep 7;261:115798.. .