Bioactivity | Antibacterial agent 154 (compound 7) is a derivative of Fluoroqinolones and is an orally effective antibacterial agent. Antibacterial agent 154 inhibits Gram-positive and Gram-negative bacteria. Antibacterial agent 154 demonstrated in vivo efficacy in a mouse model of staphylococcal sepsis[1]. |
Invitro | Antibacterial agent 154 (compound 7) 抑制革兰氏阳性菌 M. luteus,B. subtilis,S. aureus,S. epidermidis 的 MIC 分别为 4 μg/mL,2 μg/mL,2 μg/mL,2 μg/mL;抑制革兰氏阴性菌 P. aerugenosa,E. coli,S. typhimurium 的 MIC 分别为 2 μg/mL 和 2 μg/mL[1]。 0 --> Antibacterial agent 154 相关抗体: |
Name | Antibacterial agent 154 |
CAS | 2163048-45-9 |
Formula | C25H28ClFN4O5 |
Molar Mass | 518.97 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shtyrlin NV, et al. Synthesis and biological evaluation of fluoroquinolones containing a pyridoxine derivatives moiety. Eur J Med Chem. 2023 Sep 7;261:115798.. . |