| Bioactivity | Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance[1]. |
| Target | MIC50: 0.25 - 8 μM (Gram-positive pathogens) |
| Invitro | Antibacterial agent 125 对临床相关的革兰氏阳性病原体具有活性，MIC50 值为 0.25-8 μM[1]。Antibacterial agent 125 对耐甲氧西林 Staphylococcus aureus strain 菌株具有抑制活性，且在人体细胞中未表现出细胞毒性[1]。Antibacterial agent 125 具有高代谢稳定性和优异的安全性[1]。Antibacterial agent 125 传代 10 次后不产生耐药性，具有中度抑制生物膜形成的能力[1]。 |
| Name | Antibacterial agent 125 |
| CAS | 1274611-43-6 |
| Formula | C15H11ClN2O |
| Molar Mass | 270.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Francesca Brunelli, et al. Isocyanides in med chem: A scaffold hopping approach for the identification of novel 4-isocyanophenylamides as potent antibacterial agents against methicillin-resistant Staphylococcusaureus. Eur J Med Chem. 2022 Nov 26;246:114950. |
Antibacterial agent 125
CAS: 1274611-43-6 F: C15H11ClN2O W: 270.71
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against c
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