| Bioactivity | Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs Staphylococcus aureus (S. aureus). Antibacterial agent 102 also moderately inhibits CYP3A4 with an IC50 value of 6.148 μM. Antibacterial agent 102 can reduce Methicillin-resistant Staphylococcus aureus (MRSA) load in thigh infected mice[1]. |
| Target | MIC: S. aureus)IC50: 6.148 μM (CYP3A4) |
| Name | Antibacterial agent 102 |
| CAS | 2413293-65-7 |
| Formula | C35H49N5O5S |
| Molar Mass | 651.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang Z, et al. Design, synthesis and biological activities of novel pleuromutilin derivatives with a substituted triazole moiety as potent antibacterial agents. Eur J Med Chem. 2020;204:112604. |
Antibacterial agent 102
CAS: 2413293-65-7 F: C35H49N5O5S W: 651.86
Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs < 0.5 μg/
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