| Bioactivity | Anti-inflammatory agent 74 (B5) is an anti-inflammatory agent that can inhibit NO, IL-6, and TNF-α, with IC50 values of 10.88 μM and 4.93 μM for NO and IL-6, respectively. Anti-inflammatory agent 74 alleviates acute lung injury (ALI) by regulating inflammatory mediators and inhibiting the MAPK and NF-κB signaling pathways[1]. |
| Target | IC50: 10.88 μM (NO).IC50: 4.92 μM (IL-6). |
| Formula | C41H51NO14 |
| Molar Mass | 781.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo Hong-Yan, et al. "Design and synthesis of forsythin derivatives as anti-inflammatory agents for acute lung injury." European Journal of Medicinal Chemistry (2024): 116223. |
Anti-inflammatory agent 74
CAS: F: C41H51NO14 W: 781.84
Anti-inflammatory agent 74 (B5) is an anti-inflammatory agent that can inhibit NO, IL-6, and TNF-α, with IC50 values of
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