| Bioactivity | Anti-IAV agent 1 (Compound (R)-1a) is an orally active anti-influenza A virus (IAV) agent with IC50s of 0.03 and 0.06 μM against IAV H1N1 and Oseltamivir-resistant IAV H1N1 strains, respectively[1]. |
| In Vivo | Anti-IAV agent 1 (Compound (R)-1a) (1.67-15 mg/kg; p.o.; twice daily for 7 days) 在小鼠中显示出抗甲型流感病毒活性[1]。 Animal Model: |
| Name | Anti-IAV agent 1 |
| Formula | C28H28FN9O3 |
| Molar Mass | 557.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wu W, et al. Optimization and SAR research at the benzoxazole and tetrazole rings of JNJ4796 as new anti-influenza A virus agents, part 2. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114906. |