| Bioactivity | Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone[1][2]. |
| Invitro | Anthopleurin-A (2 nM-640 nM) TFA 可增强离体猫心脏乳头肌的收缩力[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Anthopleurin-A TFA 相关抗体: |
| In Vivo | Anthopleurin-A (0.2 μg/kg/min，静脉注射) TFA 可增加麻醉犬的心肌收缩力[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Sequence | Gly-Val-Ser-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Thr-Leu-Trp-Leu-Tyr-Pro-Ser-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Ala-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln (Disulfide bridge: Cys4-Cys46,Cys6-Cys36,Cys29-Cys47) |
| Shortening | GVSCLCDSDGPSVRGNTLSGTLWLYPSGCPSGWHNCKAHGPTIGWCCKE (Disulfide bridge: Cys4-Cys46,Cys6-Cys36,Cys29-Cys47) |
| Formula | C220H326N64O67S6.xC2HF3O2 |
| Molar Mass | 5131.72 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Honma T, Shiomi K. Peptide toxins in sea anemones: structural and functional aspects. Mar Biotechnol (NY). 2006 Jan-Feb;8(1):1-10. [2]. Scriabine A, et al. Cardiotonic effects of anthopleurin-A, a polypeptide from a sea anemone. J Cardiovasc Pharmacol. 1979 Sep-Oct;1(5):571-83. |
Anthopleurin-A TFA
CAS: F: C220H326N64O67S6.xC2HF3O2 W: 5131.72 (free base)
Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardioto
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