Bioactivity | Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties[1][2]. |
Invitro | Anisodamine hydrobromide (100 μg/mL; 20 minutes; RAW264.7 cells) pretreatment for 20 minutes before Ach results in significantly attenuated average fluorescence intensity of α-bungarotoxin binding compared with Ach alone[2].Anisodamine hydrobromide action might be through blockade of muscarinic receptors and thus allowing more endogenous ACh binding to the α-7nAChR[2]. |
Name | Anisodamine hydrobromide |
CAS | 55449-49-5 |
Formula | C17H24BrNO4 |
Molar Mass | 386.28 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |