| Bioactivity | Amine-PEG6-thiol hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||||||||
| Invitro | PROTAC 包含两个通过连接体连接的不同配体；一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。 PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Amine-PEG6-thiol hydrochloride 相关抗体: | |||||||||
| Formula | C14H32ClNO6S | |||||||||
| Molar Mass | 377.92 | |||||||||
| Appearance | 粘稠液体 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |