Bioactivity | Alpha 2 Macroglobulin, Human Plasma is an alpha 2 macroglobulin from human Plasma. Alpha 2 Macroglobulin is a broad-spectrum protease inhibitor. Alpha 2 Macroglobulin is also a regulator of extracellular proteolysis. Alpha 2 Macroglobulin switchs proteolysis towards small substrates. Alpha 2 Macroglobulin can be used in Alzheimer's disease, inflammation, immunity and infection research[1][2][3]. |
CAS | 403067-13-0 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Vandooren J, et al. Alpha-2-Macroglobulin in Inflammation, Immunity and Infections. Front Immunol. 2021 Dec 14;12:803244. [2]. Bauer J, et al. Interleukin-6 and alpha-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett. 1991 Jul 8;285(1):111-4. [3]. Barrett AJ, et al. The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. Biochem J. 1973 Aug;133(4):709-24. |