Bioactivity | Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders. |
Name | Adipiplon |
CAS | 840486-93-3 |
Formula | C18H18FN7 |
Molar Mass | 351.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668(1-2):190-193. [2]. Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2. |