PeptideDB

Adenosine 5'-diphosphate-15N5 dilithium

CAS: F: C10H13Li215N5O10P2 W: 444.03

Adenosine 5'-diphosphate-15N5 (Adenosine diphosphate-15N5 dilithium; ADP-15N5) dilithium is 15N labeled Adenosine 5'-dip
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Bioactivity Adenosine 5'-diphosphate-15N5 (Adenosine diphosphate-15N5 dilithium; ADP-15N5) dilithium is 15N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> Adenosine 5'-diphosphate-15N5 dilithium 相关抗体:
Name Adenosine 5'-diphosphate-15N5 dilithium
Formula C10H13Li215N5O10P2
Molar Mass 444.03
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Arts IC, et al. Adenosine 5'-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16. [3]. Noel J. Cusack, et al. Effects of phosphate-modified analogs of adenosine 5′-diphosphate and adenosine 5′‐triphosphate at P2T-purinoceptors mediating human platelet activation by ADP. April 1996. [4]. Adenosine-5'-diphosphate