| Bioactivity | Acefylline piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research[1][2][3]. |
| Invitro | Acefylline piperazine (200 μM; 5-180 min) 是有效的 PDA 激活剂[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Acefylline piperazine 相关抗体: |
| CAS | 18833-13-1 |
| Formula | C9H10N4O4.xC4H10N2 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ferretti C, et al. Inhibitory effect of theophylline, theophylline-7-acetic acid, ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992;14(1):31-6. [2]. Méchin MC, et, al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb;81(2):101-6. [3]. Tsvetkova B, Tencheva J, Peikov P. Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether. Acta Pharm. 2006 Jun;56(2):251-7. PMID: 16613730. |
Acefylline piperazine
CAS: 18833-13-1 F: C9H10N4O4.xC4H10N2 W:
Acefylline piperazine, a xanthine derivative, is anAdenosine Receptorantagonist. Acefylline piperazine is a peptidylargi
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