Bioactivity | Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate[1]. |
Name | Ac-YEVD-AMC |
CAS | 1631716-11-4 |
Sequence | Ac-Tyr-Glu-Val-Asp-{AMC} |
Shortening | Ac-YEVD-{AMC} |
Formula | C35H41N5O12 |
Molar Mass | 723.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Havira MS, et al. Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS. Sci Immunol. 2020 Nov 27;5(53):eabc0217. |