Bioactivity | Ac-VAD-AFC is a fluorescent substrate for caspases and can be used to test the activity of caspases[1][2]. |
Sequence | Ac-Val-Ala-Asp-AFC |
Shortening | Ac-VAD-AFC |
Formula | C24H27F3N4O8 |
Molar Mass | 556.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Choi WS, et al. Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2. J Neurochem. 2001;77(6):1531-1541. [2]. Posadas I, et al. Acetaminophen induces human neuroblastoma cell death through NFKB activation. PLoS One. 2012;7(11):e50160. |