| Bioactivity | Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors[1]. |
| Invitro | [3H]ac-RYYRWK-NH2 binding to rat cortical membranes revealed a single high affinity site for [3H]ac-RYYRWK-NH2 (Kd=0.071 nM)[1].Naloxone benzoylhydrazone displaced [3H]acRYYRWK-NH2 binding to rat cortical membranes (Ki=104 nM) and human ORL1 (Ki=136 nM) as well as [125I]Tyr14-NC-OH to ORL1 (Ki=37 nM) has no affinity for µ-, κ- or δ-opioid receptors[1]. |
| Name | Ac-RYYRWK-NH2 TFA |
| CAS | 408305-09-9 |
| Shortening | Ac-RYYRWK-NH2 |
| Formula | C51H70F3N15O11 |
| Molar Mass | 1126.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Ac-RYYRWK-NH2 TFA
CAS: 408305-09-9 F: C51H70F3N15O11 W: 1126.19
Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), Ac-RYYRWK-NH2 binds to rat co
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