Bioactivity | Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1]. |
Name | Ac-IEPD-AMC |
CAS | 216757-33-4 |
Sequence | Ac-Ile-Glu-Pro-Asp-{AMC} |
Shortening | Ac-IEPD-{AMC} |
Formula | C32H41N5O11 |
Molar Mass | 671.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703. |