Bioactivity | Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. Ac-GpYLPQTV-NH2 acetate has antitumor activity[1]. | ||||||
Sequence | Ac-Gly-{p-Tyr}-Leu-Pro-Gln-Thr-Val-NH2 | ||||||
Shortening | Ac-G-{p-Tyr}-LPQTV-NH2 | ||||||
Formula | C38H60N9O14P.xC2H4O2 | ||||||
Molar Mass | 897.91 (free base) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Reference | [1]. Uehara Y, et al A. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009 Mar 13;380(3):627-31. |