Bioactivity | Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product[1]. |
Name | Ac-GAK-AMC |
CAS | 1926163-46-3 |
Sequence | Ac-Gly-Ala-{Lys-AMC} |
Shortening | Ac-GA-{Lys-AMC} |
Formula | C23H31N5O6 |
Molar Mass | 473.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brian E Schultz, et al. Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. Biochemistry. 2004 Aug 31;43(34):11083-91. |