Bioactivity | ATAD2-IN-1 (compound 19f) is a potent ATAD2 inhibitor (IC50: 0.27 μM) and can induce apoptosis. ATAD2-IN-1 also inhibits c-Myc activation and BT-549 cell migration[1]. |
Target | IC50: 0.27 μM(ATAD2) |
Name | ATAD2-IN-1 |
CAS | 3004556-06-0 |
Formula | C22H26N6O5 |
Molar Mass | 454.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yao D, et al. Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2242601. |