| Bioactivity | AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes[1]. |
| Invitro | AMPK activator 8 (compound 2) acts on rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ and rAMPK α2β2γ3 with the EC50 value of 11 nM, 27 nM, 4 nM, 2 nM and 4 nM, respectively[1].AMPK activator 8 (compound 2) affects cell viability[1]. Cell Viability Assay[1] Cell Line: |
| Name | AMPK activator 8 |
| CAS | 1852451-96-7 |
| Formula | C25H21ClN2O6 |
| Molar Mass | 480.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mathilde Muzerelle, et al. Novel activators of amp-activated protein kinases.WO2016001224A1 |
AMPK activator 8
CAS: 1852451-96-7 F: C25H21ClN2O6 W: 480.90
AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC50s of 11, 27, 4, 2, and 4 nM
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