| Bioactivity | AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2]. | ||||||||||||
| Invitro | AMPA receptor modulator-3 (Compound 5e) shows an EC50 value of 4.4 μM for potentiation of responses mediated by 100 μM L-glutamate in HEK-293 cells expressing iGluR4 flip[2]. | ||||||||||||
| Name | AMPA receptor modulator-3 | ||||||||||||
| CAS | 211311-39-6 | ||||||||||||
| Formula | C18H22FNO2S | ||||||||||||
| Molar Mass | 335.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Kasper Harpsøe, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26(5):874-83. https://pubmed.ncbi.nl |
AMPA receptor modulator-3
CAS: 211311-39-6 F: C18H22FNO2S W: 335.44
AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be use
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