| Bioactivity | AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1]. | ||||||||||||
| Target | TRPM8. | ||||||||||||
| Name | AMG2850 | ||||||||||||
| CAS | 1470018-52-0 | ||||||||||||
| Formula | C19H17F6N3O | ||||||||||||
| Molar Mass | 417.35 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76. |