Bioactivity | ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM[1]. |
Target | IC50: 95 nM (ALPK1), 1.31 μM (NF-κB) |
Name | ALPK1-IN-2 |
CAS | 2765633-68-7 |
Formula | C20H18F2N4O2S |
Molar Mass | 416.44 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Danyang Liu, et al. Benzothiazole and quinoline derivatives and their use. WO2022063153A1. |