Bioactivity | ALKBH5-IN-2 (compound 6) is a potent ALKBH5 inhibitor with an IC50 value of 0.79 µM. ALKBH5-IN-2 inhibits cell viability[1]. |
Invitro | ALKBH5-IN-2 (compound 6) (0-50µM; 48 h) 抑制细胞活力,对 HEK-293T、CCRF-CEM、HL-60、Jurkat、K562、A-172 细胞的 IC50 值分别为 40.5、7.62、11.0、41.3、1.41、>50 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> ALKBH5-IN-2 相关抗体: Cell Viability Assay[1] Cell Line: |
CAS | 1008951-10-7 |
Formula | C9H11N3O3 |
Molar Mass | 209.20 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Selberg S, et al. Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors. ACS Omega. 2021 May 14;6(20):13310-13320. |