Bioactivity | (+)-Perillyl alcohol is the enantiomer of S-(-)-Perillyl alcohol (HY-116514). (+)-Perillyl alcohol can inhibit the growth of polypeptides and block the cell cycle in the G0/G1 phase. (+)-Perillyl alcohol induces cell signaling that is associated with changes in cytoskeletal actin organization and reduced protein expression of growth regulatory proteins such as Ras and CDC2 kinase[1]. |
Invitro | (+)-Perillyl alcohol (0.25-1 mM) 在 SW480 细胞中抑制细胞生长[1]。(+)-Perillyl alcohol (1 mM; 24 h)在 SW480 细胞中增加 G0/G1 细胞数量,减少 S 期细胞数量[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (+)-Perillyl alcohol 相关抗体: |
CAS | 57717-97-2 |
Formula | C10H16O |
Molar Mass | 152.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Cerda SR, et al. R-(+)-perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34(cdc2) expression in colonic adenocarcinoma SW480 cells. J Nutr Biochem. 1999 Jan;10(1):19-30. |