| Bioactivity | AKT-IN-21 (compound C36) is a potent AKT inhibitor with broad-spectrum cytotoxicity and anticancer activity. AKT-IN-21 also blocks the cell cycle and induces apoptosis of cancer cells by down-regulating the PI3K/AKT pathway[1]. |
| Invitro | AKT-IN-21 在多种癌细胞中显示出抗增殖抑制活性和细胞毒性，IC50 分别为 2.33 μM (LNCaP)、2.38 μM (K562)、1.98 μM (HepG2)、3.95 μM (LX-2)[1]。 0 --> AKT-IN-21 相关抗体: |
| Name | AKT-IN-21 |
| Formula | C26H34N2O4 |
| Molar Mass | 438.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yu J, et al. Design, synthesis and bioevaluation of novel prenylated chalcones derivatives as potential antitumor agents. Eur J Pharm Sci. 2024 Jan 1;192:106660. |