| Bioactivity | ADP-β-S trilithium is the trilithium salt form of ADP-β-S (HY-134353). ADP-β-S trilithium is the activator for P2Y12 receptor, which upregulates levels of IL-1βand IL-6 production in microglial cells, promotes the phosphorylation and nuclear translocation of NF-κB, and enhances the activation of the NLRP3 inflammasome[1]. |
| CAS | 73536-95-5 |
| Formula | C10H12Li3N5O9P2S |
| Molar Mass | 461.07 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Suzuki T, et al., Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor. Eur J Immunol. 2020 Feb;50(2):205-219. |
ADP-β-S trilithium
CAS: 73536-95-5 F: C10H12Li3N5O9P2S W: 461.07
ADP-β-S trilithium is the trilithium salt form of ADP-β-S (HY-134353). ADP-β-S trilithium is the activator for P2Y12
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