| Bioactivity | AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor with an IC50 value of 0.42 μM. AChE-IN-26 can be used for the research of Alzheimer’s disease[1]. | ||||||||||||
| Target | IC50: 0.42 μM (AChE) | ||||||||||||
| Invitro | AChE-IN-26 (1 and 10 μM;20 min) shows an in-vitro inhibition to AChE of 91.45%, and inhibits AChE with an IC50 value of 0.42 μM[1]. | ||||||||||||
| Name | AChE-IN-26 | ||||||||||||
| Formula | C21H21BrN2O3 | ||||||||||||
| Molar Mass | 429.31 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Abdullaha M, et al. Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur J Med Chem. 2020 Dec 1;207:112761. |