PeptideDB

ACSS2-IN-2

CAS: 2332820-04-7 F: C21H19F2N3O4 W: 415.39

ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activit
Data collection:peptidedb@qq.com

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Bioactivity ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1].
Target IC50: 3.8 nM (ACSS2)
Invitro ACSS2-IN-2 (Compound 261) (5 h) has ACSS2 inhibitory activity with an IC50 value of 3.8 nM in MDA-MB-468 cells[1].
Name ACSS2-IN-2
CAS 2332820-04-7
Formula C21H19F2N3O4
Molar Mass 415.39
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Philippe Nakache, et al. Acss2 inhibitors and methods of use thereof. Patent. WO2019097515A1.