| Bioactivity | A80.2HCl is a MYC degrader that restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance. A80.2HCl has antitumor activity[1]. |
| CAS | 2946670-96-6 |
| Formula | C32H31ClF3N5O3 |
| Molar Mass | 626.07 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ma J, et al. MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation. Nat Commun. 2024 Feb 29;15(1):1871. |
A80.2HCl
CAS: 2946670-96-6 F: C32H31ClF3N5O3 W: 626.07
A80.2HCl is a MYC degrader that restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance. A80.2HCl has
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