| Bioactivity | A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1]. | ||||||||||||
| Target | Ki: 4 nM (adenosine A2A receptor), 264 nM (A1 receptor) | ||||||||||||
| Invitro | A2A receptor antagonist 1 (CPI-444 analog) is a potent adenosine A2A receptor antagonist, selective over the A1 receptor and demonstrates its binding activity with Ki values of 4 and 264 nM, respectively[1]. | ||||||||||||
| Name | A2A receptor antagonist 1 | ||||||||||||
| CAS | 443103-97-7 | ||||||||||||
| Formula | C16H12FN5O | ||||||||||||
| Molar Mass | 309.30 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Gillespie RJ, et al. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9. |
A2A receptor antagonist 1
CAS: 443103-97-7 F: C16H12FN5O W: 309.30
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist ofboth adenosine A2A receptor and A1 receptor with Ki values
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