| Bioactivity | 7α,15-Dihydroxydehydroabietic acid is a natural abietane-type diterpenoid with antiangiogenic effects[1]. |
| Invitro | 7α,15-Dihydroxydehydroabietic acid（3.125-100 μM；24 小时）显着降低 HUVEC 细胞活力[1]。7α,15-Dihydroxydehydroabietic acid (3.125-6.25 μM; 24 小时) 显着抑制 HUVEC 中血管生成的促进作用。7α,15-Dihydroxydehydroabietic acid 通过下调 VEGF、p-Akt 和 p-ERK 信号通路抑制血管生成[1]。 Cell Viability Assay[1] Cell Line: |
| Name | 7α,15-Dihydroxydehydroabietic acid |
| CAS | 155205-64-4 |
| Formula | C20H28O4 |
| Molar Mass | 332.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tae Kyoung Lee, et al. 7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1084-1089. |
7α,15-Dihydroxydehydroabietic acid
CAS: 155205-64-4 F: C20H28O4 W: 332.43
7α,15-Dihydroxydehydroabietic acid is a natural abietane-type diterpenoid with antiangiogenic effects.
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