PeptideDB

7-Hydroxymitragynine

CAS: 174418-82-7 F: C23H30N2O5 W: 414.49

7-Hydroxymitragynine, an active metabolite of Mitragynin, is a potent and G protein-biased partial agonist of the µ-opi
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Bioactivity 7-Hydroxymitragynine, an active metabolite of Mitragynin, is a potent and G protein-biased partial agonist of the µ-opioid receptor, with an EC50 of 34.5 nM. 7-Hydroxymitragynine can be used for the research of pain[1][2].
Target EC50: 34.5 nM (µ-opioid receptor)
Name 7-Hydroxymitragynine
CAS 174418-82-7
Formula C23H30N2O5
Molar Mass 414.49
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kruege AC, et, al. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. ACS Cent Sci. 2019 Jun 26;5(6):992-1001. [2]. Todd DA, et, al. Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions. Sci Rep. 2020 Nov 5;10(1):19158.