| Bioactivity | 7-Hydroxymitragynine, an active metabolite of Mitragynin, is a potent and G protein-biased partial agonist of the µ-opioid receptor, with an EC50 of 34.5 nM. 7-Hydroxymitragynine can be used for the research of pain[1][2]. |
| Target | EC50: 34.5 nM (µ-opioid receptor) |
| Name | 7-Hydroxymitragynine |
| CAS | 174418-82-7 |
| Formula | C23H30N2O5 |
| Molar Mass | 414.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kruege AC, et, al. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. ACS Cent Sci. 2019 Jun 26;5(6):992-1001. [2]. Todd DA, et, al. Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions. Sci Rep. 2020 Nov 5;10(1):19158. |